There are few online reviews for Protandim; for example, as of December 2015, there are five reviews for Protandim on Amazon.com, each of which give the product between three and five stars. Though few, the written comments for the product on Amazon.com are uniformly positive, and the rater who gives the product three stars makes a negative comment about the quality of service from Amazon.com rather than about Protandim itself.
Users of Protandim also write highly positive comments about the effectiveness of this supplement on blogs describing the product, such as The Medicine Guy and Supplement Geek. Two reviewers on The Medicine Guy, for example, credit Protandim for improving their muscular dystrophy symptoms, with one specifying that the supplement reduced her pain levels and improved her incontinence and balance. Another reviewer on this site noted a drop in triglycerides and bad cholesterol, thicker hair, stronger nails and better skin after taking Protandim for two months. In addition, a reviewer on Supplement Geek states that this supplement improved her chronic lyme disease symptoms.
A mixture of different plant ingredients comprise protandim, including green tea and tumeric, and a clinical study showed that it reduces oxidative stress, which may slow the body's aging process, according to LifeVantage. However, while the reviewers above emphasized its effectiveness in treating their chronic illnesses, Protandim does not claim to treat, cure or prevent any disease.