What Is an Inverted Papilloma?


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An inverted papilloma is a benign epithelial tumor that originates in the nasal cavity and the paranasal sinuses, according to the University of Pittsburgh Medical Center. Inverted papillomas have a close relation to squamous cell carcinoma, a condition that may be present in the initial diagnosis or occur after prior treatment, notes the National Center for Biotechnology Information.

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Although benign, the fingerlike projections in inverted papillomas may grow inward within the nose and become cancerous, explains the University of Pittsburgh Medical Center. Doctors identify inverted papillomas through their reddish-grey appearance and the presence of symptoms such as sinusitis, nosebleed, runny nose and nasal obstruction. Inverted papillomas lead to facial pain, frontal headache, loss of sense of smell, and may bleed when touched.

Magnetic resonance imaging helps to identify the extent of inverted papilloma spreading or any resulting bone destruction, notes the UPMC. Doctors follow up the diagnosis of inverted papilloma with biopsies to make definitive diagnoses. Surgery is the preferred treatment option for inverted papilloma, although the condition has up to a 50-percent probability of recurring, according to the NCBI. The success rate of curing malignant inverted papilloma is 50 percent, whereby doctors have to carry out postoperative therapy. Squamous cell carcinoma raises the probability of inverted papilloma recurring or causing death.

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