The active ingredient in Prevagen is apoaequorin, and the inactive ingredients are white rice flour, cellulose, salt, vegetable sourced magnesium stearate and acetic acid, according to Prevagen.com. Apoaequorin is a protein originally collected from a species of jellyfish in the Puget Sound.
Apoaequorin is a protein the brain needs to properly function, but it diminishes with age, claims Prevagen.com. However, the Food and Drug Administration issued a warning letter in 2012 to the company that sells Prevagen, Quincy Bioscience Manufacturing, Inc. In the letter, the FDA stated that Quincy Bioscience had been illegally conducting a clinical trial without an approved application, making the investigation and marketing of the company's products illegal.
Additionally, there was a class-action suit filed against Quincy Bioscience over its marketing of the memory supplement, explains Consumer Health Digest. The complaint charged that the company's claims that the product works by supplying memory-related proteins to the brain cannot be true because its only supposed active ingredient is completely destroyed by digestion and transformed into amino acids that can easily be derived from many other foods. The suit further alleged that the quantities of the amino acids that Prevagen supplies are also trivial in comparison to a person's normal dietary intake, and it stated that claims about scientific evidence from clinical tests are false.