GNC Total Lean CLA contains 2,000 milligrams of conjugated linoleic acid from safflower oil, along with glycerin and gelatin, states GNC. The supplement does not contain sugar, starch, wheat, gluten or corn. In addition, GNC Total Lean CLA does not contain preservatives, sodium, soy, dairy, or artificial colors or flavors.
Conjugated linoleic acid is possibly an effective supplement for treating high blood pressure and obesity, according to WebMD. The supplement may decrease body fat, but it typically does not decrease weight or body mass index. Some people who take conjugated linoleic acid experience reduced feelings of hunger. Although some people take conjugated linoleic acid for allergies, asthma, rheumatoid arthritis and certain types of cancer, not enough scientific evidence exists to rate the supplement's effectiveness for these conditions.
Taking conjugated linoleic acid supplements sometimes causes side effects such as diarrhea, nausea, fatigue and upset stomach, notes WebMD. Individuals with diabetes or metabolic syndrome should not take conjugated linoleic acid supplements because they may worsen these conditions. Taking this supplement may also slow blood clotting, so individuals should stop taking it at least two weeks prior to surgery. Women who are pregnant or breastfeeding should not take conjugated linoleic acid for medicinal purposes because of limited scientific studies.