A high corpuscular hemoglobin count indicates the body's red blood cells are larger than usual, typically as a result of anemia caused by myelodysplasia, liver disease, vitamin B12 deficiency, hypothyroidism or folate deficiency, notes Lab Tests Online. The mean corpuscular hemoglobin, or MCH, count measures the average number of hemoglobin inside one red blood cell.
A high MCH count may also indicate certain infections, consumption of too many medications containing estrogen, certain forms of leukemia and hereditary spherocytosis, states Health Testing Centers. Patients undergoing chemotherapy may also have higher than normal levels. The MCH is equal to the hemoglobin value divided by the number of red blood cells in the blood, according to Health Testing Centers. The normal level of MCH in the body ranges from 26 to 33 picograms of hemoglobin per red blood cell, and an MCH calculation is typically completed as part of a Complete Blood Count.
A complete blood count, or CBC, evaluates white blood cells, red blood cells and platelets, states Lab Tests Online. A CBC screens for diseases; helps diagnose certain conditions, such as bleeding disorders and infections; helps monitor a condition and the treatment for the condition; and monitors treatments such as chemotherapy and radiation therapy, which affect the body's blood cells. A CBC directly measures the amount of hemoglobin, red blood cells and hematocrit, or the percentage of the blood volume composed of red blood cells, and uses these measurements to determine MCH, the mean corpuscular volume, and the mean corpuscular hemoglobin concentration.