Immunoglobulin A, or IgA, nephropathy is an inflammatory disease of the kidneys where the kidneys have difficulty filtering waste, electrolytes and water from the blood, states Mayo Clinic. Known as Berger's disease or glomerulonephritis, IgA nephropathy has no cure as of 2015, but treatments can prevent progression of the disease.
IgA nephropathy damages kidney function due to the accumulation of the IgA protein in the glomeruli, which act as the filters of the kidneys, states the National Kidney Foundation. This loss of kidney function often leads to kidney failure.
Treatment of IgA nephropathy includes dietary changes, such as limiting protein intake, and blood pressure control, notes the National Kidney Foundation. Doctors prescribe corticosteroids to control the progression of the disease.