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What is hyperplastic polyposis?

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Hyperplastic polyposis is a condition in which there is a large number of hyperplastic polyps in the colon, explains Johns Hopkins Medicine. Doctors usually make the diagnosis in individuals with over 20 of these colon polyps, but patients with fewer polyps may receive the diagnosis if the polyps are large.

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Patients with a hyperplastic polyposis diagnosis can have six to more than 100 hyperplastic polyps, according to Johns Hopkins Medicine. The condition is most prevalent in patients in their 40s, 50s and 60s, but doctors have seen it in patients as young as 11.

As of 2015, the available research does not suggest hyperplastic polyps are a significant precursor of colorectal cancer, although further research into the topic is necessary, notes Johns Hopkins Medicine. Still, the risk of developing colorectal cancer is higher in patients with hyperplastic polyposis than those who do not have the condition, so it is important to receive routine cancer screenings following diagnosis.

Over 95 percent of cases of colorectal cancer originate as adenomas, another type of colon polyp, states Johns Hopkins Medicine. However, the presence of adenomas in the colon does not guarantee progression to colorectal cancer, as under 10 percent of adenomas become malignant.

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