As rated by pharmacists, Afrin is the nasal decongestant with the highest votes, according to a U.S. News Health report. This decongestant received a rating of 75 percent from pharmacists' votes. Some other decongestants on this list are Neo-Synephrine, NasalCrom and Mucinex nasal spray.
Nasal decongestants contain active ingredients that reduce blood vessel inflammation in the nasal cavities, which allows a person to breathe better. The active ingredient in Afrin is oxymetazoline and phenylephrine is found in Neo-Synephrine, states The Washington Post. Afrin can help with nasal congestion for up to 12 hours.
These over-the-counter nasal sprays are useful. However, it is important not to overuse these products. They should not be used for longer than 3 days, notes Family Doctor. When nasal decongestants are utilized for longer than this period of time, they can make the nasal cavities feel stuffier.