The top-rated over-the counter decongestants are Sudafed, Claritin D, Mucinex-D, Sudafed PE, Zyrtec-D and Tylenol Sinus, based on a survey of pharmacists conducted by The Pharmacy Times in conjunction with U.S. News & World Report. Decongestants are used when sinuses are congested and stuffy while antihistamines are recommended for allergies. Symptoms, treatments and results vary by individual and talking to a doctor for treatment is recommended, especially if symptoms last longer than 2 weeks.
Decongestants come in the form of pills, liquids, nose drops and nasal sprays. Many are available without a prescription including Afrin, Dristan and Vicks Sinex. Users should not use nasal sprays longer than 3 days in order to prevent further nose congestion, notes WebMD.