Side effects that may occur when a person stops taking Premarin include night sweats, irritability, hot flashes and vaginal dryness, according to Elizabeth Hanes, a general medicine nurse writing for WebMD. Ceasing hormone treatments may also put women at increased risk for high blood pressure, reports Reuters Health.
In a study conducted by The North American Menopause Society, it was concluded that cessation of hormone therapy may cause some women to experience hypertension, and their quality of life may be negatively affected in other ways.
Premarin, a brand of hormone replacement therapy, is often used to replace estrogen in women with ovarian problems or other conditions that alter the estrogen levels in their body, explains Everyday Health. The drug is also used to help prevent osteoporosis and to treat symptoms of menopause.
Many women who stopped taking hormone therapies such as Premarin because of reported risks eventually restart because the severe withdrawal symptoms affected their quality of life, according to Dr. JoAnn Pinkerton, a medical director at the University of Virginia in Charlottesville. When considering whether or not to continue taking Premarin or other types of hormone replacement therapy, Dr. Pinkerton recommends that women talk with a menopause specialist to discuss options for dealing with their symptoms.