Grumbling appendix is a condition in which the patient has recurrent appendix pain in the absence of inflammation as well as an elevated white blood cell count, according to Kidspot. Grumbling appendix sometimes progresses to appendicitis.
It's important to watch for signs of appendicitis in patients suffering from grumbling appendix, Kidspot notes. Symptoms of appendicitis may include pain around the navel that moves to the lower right abdomen, fever, nausea, vomiting and diarrhea. Immediate medical attention is important, because acute appendicitis can cause the appendix to rupture. Treatment for appendicitis is an appendectomy, or removal of the appendix, to prevent rupture and a subsequent, life-threatening infection.