Treatment for Fordyce spots, such as laser treatment, is purely cosmetic, as explained by Medical News Today. A simpler treatment, according to Patient Help, is a cream or gel, called Tretinoin, or a chemical peel called trichloroacetic acid, which should not be used on the lips.
More natural treatments include, increasing the dietary intake of vitamins A, B, C, D, E and K or rubbing with natural oils, such as jojoba, notes Patient Help. Fordyce spots are not an infection but a type of gland in the wrong place, according to Medical News Today. They are abnormally dilated blood vessels covered in a thick skin. The spots can go away without treatment but may also recur.