Medications that relieve sinus headaches include acetaminophen and ibuprofen, as well as triptans such as sumatriptan and zolmitriptan, according to Mayo Clinic. Medications such as chlorpromazine and metoclopramide, which treat nausea, also relieve sinus headaches. When the headache persists for three days or more, ergots can be used.
A sinus headache is a pain that results from sinusitis, which is an infection in the sinuses, as Mayo Clinic explains. The symptoms of a sinus headache include pressure in the region around the eyes, forehead and cheeks. In most cases, patients with sinus headaches usually experience migraines, which are tension-related headaches.