Over-the-counter medications such as topical creams, acetaminophen, ibuprofen and aspirin are all recommended for nerve pain in the foot, according to WebMD. Some patients also find nerve pain relief with supplements such as vitamin B-12.
There are many over-the-counter topical treatments that are marketed to treat nerve pain, claims WebMD. Some of these creams and gels contain capsaicin, the same ingredient that makes peppers taste hot. Others contain botanical oils. Pills and supplements are also available to treat nerve pain in the foot, but may only be useful for pain that is mild or moderate. For pain that is not relieved by aspirin, acetaminophen or ibuprofen, it is recommended to use stronger pain relievers from a doctor.