Nerve pain can be treated with antidepressants, anticonvulsants, narcotic pain medications and topical treatments, according to WebMD. Combination therapies are also used to treat neuropathic pain when a single medication isn't effective.
The medications involved in the treatment of neuropathic pain are generally prescribed "off label," notes MedicineNet. Off-label use means that the drugs were initially approved by the FDA for other conditions and were shown effective for nerve pain at a later time. For example, both tricyclic antidepressants and selective serotonin reuptake inhibitor antidepressants have proven useful for treating nerve pain. Anti-seizure medications, such as gabapentin or carbamazepine, are also powerful medications for nerve pain.
Nerve damage can be caused by diabetes, fibromyalgia, chemotherapy, trauma and infections, explains Mayo Clinic. The burning, stinging and shooting pain associated with neuropathy can be difficult to treat.