When a hot grease burn occurs, rinse the burned skin with cool water to lower the skin temperature. Do so until the pain stops, usually for 15 to 30 minutes.
Do not touch a hot grease burn to prevent the open blisters from becoming infected. Do not break any of the blisters, and clean the area with lukewarm water and a mild soap. Use a bandage for the burned area and change it daily. For serious burns, a doctor may recommend the use of an antibiotic ointment, according to WebMD.com. After applying the ointment, cover the area with sterile gauze and change it as required.