Glipizide is prescribed as a treatment for Type 2 diabetes and generally accompanies diet and exercise. Patients should use glipizide only as directed. They should also report any serious side effects to the prescribing physician, who then adjusts the dosage or discontinues it entirely, according to Drugs.com.
Glipizide is prescribed as an immediate release, extended release or a combination oral dose for adults. The immediate release dosage is a one-time release. If the one-time dose is not effective, the treatment can be extended, with the initial doses at 5 mg per day, according to Drugs.com. While taking a combination dosage of glipizide, the doctor closely monitors the patient for the development of hypoglycemia, or low blood sugar levels, as the dosage is according to the body's reaction to the dose, as Drugs.com explains.
Patients switching from insulin to glipizide should stop taking insulin and switch to the prescribed amount of glipizide if their insulin dosage is equal to or less than 20 units, according to Drugs.com. For patients taking more than 20 units of insulin, the dosage of insulin should be decreased by half and then supplemented with the prescribed amount of glipizide. The physician adjusts the dosage according to the patient's reaction to the reduction in insulin. Adhering to the physician's instructions for taking glipizide allows the physician to monitor and make the necessary adjustments in the dosage, preventing serious side effects, as Drugs.com explains.