According to the American Cancer Society, GIST cancer is a type of gastrointestinal cancer that causes stromal tumors in the digestive tract. The tumors begin in the interstitial cells of Cajal and most often form in the stomach first before moving to other parts of the digestive tract.
Gastrointestinal stromal tumors can begin anywhere in the digestive tract, as the American Cancer Society explains. GIST cancer is only one type of cancer that can affect the digestive system. The human gastrointestinal tract begins in the mouth and ends at the anus, and it contains a variety of cells, tissues and organs that are susceptible to cancer, according to the American Cancer Society.