Drugs.com explains that research supports claims that garcinia cambogia is beneficial for promoting weight loss and lipid-lowering activity; however, there have not been a high number of trials performed on the supplement. The main medicinal component in garcinia cambogia is HCA, which is said to inhibit the conversion of glucose into fatty acids.
WebMD describes it as being potentially safe for use with no known long-term side effects. However, it is known to cause nausea, digestive tract discomfort and headaches. Because few studies have been done on the plant, it is not recommended for pregnant or breastfeeding women.
K. Aleisha Fetters of Women's Health reports that a fraudulent publisher used the Women's Health brand as part of scam targeting dieters using garcinia cambogia in 2013. Although the fruit itself is healthy, studies found that high doses of the rind caused testicular atrophy and toxicity among mice. Diet pills containing the compound have failed laboratory testing, but because it is classified as a supplement, the FDA does not oversee industry regulations. Fetters points out that even if garcinia cambogia's rind is safe to consume, nothing is preventing diet pill manufacturers from combining it with more harmful substances.
According to Fetters, garcinia cambogia gets its reputation as a weight loss supplement because of the high doses of hydroxycitric acid found in its rind, which is supposedly responsible for decreasing appetite and preventing the body from storing fat.
WebMD states that while research suggests garcinia cambogia may prevent fat storage and aid in appetite control, there is insufficient evidence these effects occur in humans.Learn more about Vitamins & Supplements