There is insufficient evidence for the efficacy of GABA for weight loss, according to WebMD. Although often marketed as a fat-burning supplement, there is no scientific proof as to its effectiveness, as of 2015.
Proponents of GABA use say that it promotes lean muscle growth and increases exercise intolerance while increasing lean body weight and decreasing body fat, notes WebMD. However, these benefits of GABA also lack sufficient scientific proof.
GABA supplements are possibly effective in reducing blood pressure, notes WebMD. Some studies show that taking GABA supplements may also be useful in slowing the onset of motion sickness and reducing symptoms of pale skin, cold sweats and chills associated with the condition.