How Does Fosamax Work to Treat Bone Density Disorders?


Quick Answer

Fosamax works to treat bone density disorders because a chemical component of the drug inhibits bone resorption, according to the Open Chemistry Database. The component is called alendronate sodium, which is a bisphosphonate. As an inhibitor of this nature, bisphosphonates essentially bind to a component found in bone, resulting in successful treatment for common bone resorption diseases such as osteoporosis.

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Fosamax is a calcium regulator that is available by prescription, reports the Open Chemistry Database. Fosamax, or alendronate sodium, also reduces the number of fractures among individuals with bone density issues. This includes vertebral compression fractures and hip fractures. Fosamax is commonly used to increase bone mass in men who have osteoporosis, while it is commonly used to maintain bone mass and reduce the risk of future fracture among postmenopausal women.

Additionally, alendronate sodium is a common treatment for individuals with Paget's disease, explains the Open Chemistry Database. Typically, these individuals have a bone alkaline phosphatase at least two times higher than the normal limit, or they are symptomatic. In some cases, individuals at risk for developing Paget's disease are prescribed Fosamax. Among other potential side effects, alendronate sodium can cause local irritation of the upper gastrointestinal mucosa, as well as various negative esophageal disorders. This includes esophagitis, esophageal ulcers and esophageal erosions.

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