An elevated creatine phosphokinase or CPK level is indicative of many conditions, but it is not related to fibromyalgia, according to University of Washington Department of Orthopaedics and Sports Medicine. Fibromyalgia often mimics other muscular disorders, and for this reason, a CPK test is done to rule out other conditions.
Fibromyalgia is a condition that causes generalized muscle pain and fatigue throughout the body, while CPK is an enzyme found mainly in the heart, brain and skeletal muscles, states MedlinePlus.
Causes of elevated CPK levels include muscular dystrophy, brain injury, heart attack or stroke, explains Healthgrades. High CPK levels are also seen in people who have experienced electric shock, convulsions, death of lung tissue or inflammation of the heart.