Treatment with the oral medication Clomid may be tried before moving on to intrauterine insemination (IUI), according to Shady Grove Fertility Center in Washington, DC. Clomid stimulates the pituitary gland to release more of the body's own fertility hormones. The drug can be taken in one of two ways.
In the typical first-line treatment, Clomid is taken for five days during the menstrual cycle to induce ovulation, then the couple has intercourse when ovulation occurs. Sometimes identifying the exact time of ovulation can be difficult, so the second Clomid treatment option adds cycle monitoring, explains Shady Grove Fertility Center. Over the course of several appointments, hormone development and egg growth are monitored. The benefit of this method is the ability to time intercourse to better coincide with ovulation. After the third or fourth cycle, success rates with Clomid start to decline, making conception more difficult.
Before beginning any treatment, Shady Grove Fertility Center recommends baseline testing by a fertility specialist. This work-up should include hormone level testing to determine fertility potential and a hysterosalpingogram to confirm that the fallopian tubes are not blocked. Since 40 to 50 percent of all infertility problems are on the male's side, it is also important to get a semen analysis to check sperm for normal parameters.