While the precise pathophysiology of post-stroke late epileptic seizures is unclear, they are associated with persistent changes in the excitability in neurons and gliotic scarring, according to the U.S. National Library of Medicine. Perinatal birth trauma can also cause post-stroke seizures in children.
The severity of the initial neurological deficit is known to affect the risk of late epileptic seizures in post-stroke patients, according to the U.S. National Library of Medicine. The severity of the patient's persistent disability after the stroke also affects the risk of seizure recurrence, as does the involvement of multiple lesion sites. Additionally, large lesions and cortical damage are known to play a part in the incidence of post-stroke late epileptic seizures.
Statistically, males are more significantly more susceptible to post-stroke late epileptic seizures, according to the U.S. National Library of Medicine. The same is true of individuals with lesions on cortical tissue in the brain. Despite these facts, the incidence of cerebral hemorrhage is not a significant risk factor. Individuals who have suffered from subarachnoid brain hemorrhage can predict the likelihood of late epileptic seizure incidence through the incidence of middle cerebral artery aneurysm or intraparenchymal haematoma. EEG abnormalities also affect the possibility of post-stroke late epileptic seizure occurrence.