Vitamin B12 is one natural remedy that consumers use to treat tiredness, according to WebMD. The list also includes other natural remedies for fatigue, such as American ginseng, astralagus, black currant, evening primrose oil and melatonin.
Consumers who choose to take vitamins and natural remedies for tiredness should consult with their physicians or other health care providers and follow all instructions provided by the manufacturer of the supplements. Patients should never disregard advice from qualified medical professionals based on information provided by online resources, cautions WebMD. Those taking supplements should take precautions when consuming natural remedies, which have the potential for side effects and interactions.