What is an example of a natural PDE5 inhibitor?


Quick Answer

Horny goat weed is a natural PDE inhibitor, according to the clinical trials carried out by the University of Milan. Named Epimedii herba scientifically, this plant can be found in the wilds of Europe and Asia especially China.

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Full Answer

Horny goat weed contains icariin, a flavonol glycoside, which inhibits PDE5 and PDE4, as mentioned by NCBI. Men in China have been using horny goat weed for ages to improve their sexual performance and drive.

Viagra, Cialis and Levitra are three commonly used drugs that act as PDE5 or phosphodiesterase-5 inhibitors, as noted in an article in The New York Times. They inhibit the PDE-5 enzyme, which allows the penis to relax and experience more blood flow, solving the problem of ED or erectile dysfunction in men. There are side effects to taking these drugs especially for those suffering from ailments like severe heart diseases and hypertension.

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