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What is end stage multiple myeloma?

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Quick Answer

End stage multiple myeloma is the final stage of advanced multiple myeloma. According to MedlinePlus, the symptoms of end stage multiple myeloma include vomiting, nausea, urination problems, numbness in legs and constipation.

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Full Answer

Multiple myeloma often times originates in the bone marrow and is similar to diseases such as leukemia and lymphoma. WebMD states that currently there is no cure for multiple myeloma and that the treatments move slowly in dealing with the disorder. During the early stages of multiple myeloma, no symptoms may be apparent. As the disease begins to move forward, symptoms include weight loss, kidney problems, bone pain due to lytic bone disease, anemia, confusion, excessive thirst from hypercalcemia, and infections. In rare cases, purple masses, known as extramedullary plasmacytomas, can develop beneath the skin.

According to WebMD, risk factors that can make people more vulnerable to multiple myeloma include being male, over 65 years of age, African-American, and having family members who have been afflicted by the disease. Those that have been diagnosed with solitary plasmacytoma, or monoclonal gammopathy of uncertain significance (MGUS), are also at risk for developing mutlple myeloma. During lab tests, indicators of multiple myeloma are anemia, protein in urine, elevated creatine, and high blood calcium.

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Related Questions

  • Q:

    Is multiple myeloma curable?

    A:

    As of September 2014, there is no known cure for multiple myeloma, according to Mayo Clinic. However, there are a number of treatments that can be used to stabilize the condition and slow its progress. These include targeted drug therapy, chemotherapy, corticosteroids, stem cell transplantation and radiation therapy.

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  • Q:

    What causes multiple myeloma?

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    The exact cause of multiple myeloma is not known as of 2015, states Mayo Clinic. Normally, multiple myeloma begins as a condition called monoclonal gammopathy, or MGUS, which is benign. Approximately 1 percent of people with MGUS develop multiple myeloma.

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    How long can someone with stage-three multiple myeloma live without taking chemotherapy?

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    A person suffering with stage-three multiple myeloma cannot expect to live much longer than 29 months with or without chemotherapy treatments, explains Healthline. As of 2015, no cures exist for this type of cancer, although prognosis for early stages are better than for late stages.

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    What are the stages of multiple myeloma?

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    According to the American Cancer Society, there are three stages of multiple myeloma. Stage one is characterized by a relatively small presence of myeloma cells, stage two is characterized by a moderate number of myeloma cells, and stage three is characterized with a large volume of cancerous cells.

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