Effective treatments for impetigo include oral antibiotics such as erythromycin and cloxacillin, antibiotic creams such as fusic acid and mupirocin, and disinfectants, according to PubMed Health. Health experts don't agree on a standard treatment or the best intervention for impetigo, a contagious bacterial skin infection commonly found in children.
Evidence shows antibiotic skin creams are significantly more effective than disinfectants in treating impetigo, states PubMed Health. In cases of limited infection, the topical creams mupirocin and fusidic acid match the effectiveness of oral antibiotics. Mupirocin surpasses oral erythromycin in effectiveness, but oral penicillin is not effective. Patients who use cream treatments may experience mild, low-frequency side effects. Disinfectant solutions are the least effective of the remedies.