The most effective cure for a minor staph infection is treatment with antibiotic ointment or oral antibiotics, according to MedicineNet. Severe staph infections may require intravenous antibiotics, while staph infections involving abscesses may require surgical draining, and deeply affected tissues may require surgery.
Minor staph infections in the skin are generally recognized by their appearance and treated with an antibiotic ointment; however, some skin infections require treatment with an oral antibiotic. Intravenous antibiotics are administered to patients with life-threatening staph infections. The treatment of severe staph infections may involve the use of laboratory testing to determine the appropriate antibiotic to eliminate the bacterial infection. Tissue, blood and body fluids may be cultured as part of the laboratory testing, reports MedicineNet. These diagnostic tests are commonly used for patients who have staph infections of the bloodstream or who have pneumonia or endocarditis.
The type of antibiotic used to treat a staph infection depends upon how drug-resistant a specific bacteria is and the severity of the infection being treated. Vancomycin, telavancin and oxacillin are among the types of antibiotics used to treat staph infections. Doctors may also use sulpha drugs to treat a staph infection. In some cases of deep staph infections affecting muscles, surgical treatment is necessary to rid the body of the infection, explains WebMD. As of 2015, staph infections are becoming increasingly resistant to antibiotic treatment, according to MedicineNet.