E. coli is not an ESBL, or an extended-spectrum β-Lactamases, according to the Centers for Disease Control. E. coli is a type of bacteria, while ESBL is an enzyme that causes resistance to certain drugs, such as penicillin, cephalosporins and aztreonams.
The E. coli bacteria can produce ESBL, according to the Centers for Disease Control and the National Institutes of Health. This is troublesome because it is difficult to treat a patient with an infection caused by ESBL producing E. coli. These bacteria resist numerous antibiotics, making it difficult for doctors to manage the course and outcomes of infections, according to the NIH.