The average dose of clindamycin for an infection is 150 to 300 mg by mouth every six hours, according to Drugs.com. For more severe infections, the dose is increased to between 300 and 450 mg by mouth every six hours.
Individuals should always take medicine exactly as it is prescribed by the doctor, states Drugs.com. Clindamycin should also be used for the exact length of time prescribed, even if symptoms improve or disappear. Skipping doses increases the chance of developing further infections that are resistant to treatment and much harder to get rid of. People who are taking the tablet form of this drug should take it with a full glass of water.