Are There Any Diseases That Cause Folic Acid Levels to Elevate?

Are There Any Diseases That Cause Folic Acid Levels to Elevate?

High folic acid levels sometimes occur in people who have pernicious anemia, a rare disorder that causes a deficiency of vitamin B-12, according to WebMD. The human body needs vitamin B-12 to utilize folic acid, so when vitamin-B-12 levels are low, folic acid levels often rise.

Pernicious anemia is a disease that prevents the body from absorbing vitamin B-12, states WebMD. People with the disease lack intrinsic factor, a protein normally found in the intestines, and cannot absorb vitamin B-12 from food. Since vitamin B-12 is essential for the maturation of red blood cells, these people develop a form of anemia, with symptoms of pallor, tiredness, weakness and fatigue. Treatment consists of vitamin-B-12 injections or pills, the National Heart, Lung and Blood Institute explains.

Other factors and illnesses also cause vitamin-B-12 deficiency. These include chronic alcoholism, Crohn's disease, short-bowel syndrome and a vegan diet, explains Medical News Today.