Dysplasia is a complication of both gastroesophageal disease, commonly referred to as GERD, and Barrett's esophagus, according to the Boston Medical Center. Barrett’s esophagus occurs when the valve between the esophagus and stomach no longer properly functions. The condition develops as a result of chronic GERD.
Although high-grade dysplasia rarely produces symptoms on its own, the loss of heartburn symptoms in persons suffering from GERD indicates the development of Barrett’s esophagus, claims the Boston Medical Center. Without receiving proper treatment, patients suffering from high-grade dysplasia often develop cancer, as the condition significantly increases the risk for esophageal adenocarcinoma. Treatment options for high-grade dysplasia include endoscopic resection, Barrx or radiofrequency ablation, esophagectomy, and photodynamic therapy.