Autoimmune diseases such as dermatitis herpetiformis, pemphigus and bullous pemphigoid can cause blisters, states WebMD. Certain viruses may cause infections, leading to blisters, according to Healthline.
Dermatitis herpetiformis is a severe inflammatory condition that occurs due to allergic reactions to gluten. The disease may cause small blisters to form on the back of the head, buttocks, lower back, elbow and knees that itch. In rare occasions, blisters may form on the face and neck. Avoiding foods that contain barley, wheat, oats and rye and taking certain medications may treat the problem.
Pemphigus is a rare, serious disease that may trigger an outbreak of blisters around the mouth, vagina, penis and general skin, according to WebMD. A plasma-exchange procedure, also known as plasmapheresis, may help counter disease as well. Bullous pemphigoid forms red or swollen blisters that are hard, tight and itchy. The disease doesn't cause blisters around the mouth. Immunosuppressants may treat the diseases and cure the blisters.
Shingles and chickenpox are caused by the same virus and may cause itchy blisters to break out on the skin, notes Healthline. Shingles occurs together with rashes and may reappear when a person is older. Herpes, impetigo and erysipelas, which result from an infection by streptococcus bacteria, may also cause blisters.