While low-grade follicular lymphoma generally has a good prognosis, the outlook in regard to a diffuse growth pattern is not clear and doesn't have clinical relevance, according to the National Institutes of Health. Many factors affect the prognosis for individuals with follicular lymphoma, explains the American Cancer Society.
Some factors that have a direct impact on survival for patients with non-Hodgkin lymphoma include other health problems and what treatment is received, the American Cancer Society states. Current survival rates or prognosis are based on five-year survival rates of people in the late 1980s and 1990s. Therefore, advances in the treatment cannot be considered when survival rates are calculated, and current survival rates are likely higher than reported.
Some factors that indicate a good prognostic outlook for follicular lymphoma include the person's age being 60 or younger, having four or less lymph node areas affected, the lymphoma being at stage l or stage ll, and having a normal serum LDH level, according to the American Cancer Society. Individuals with follicular lymphoma are divided into three groups in regard to prognosis with a point system. Each group is considered low risk, intermediate risk or high risk in terms of five- and 10-year survival. It's important to note that many patients live well beyond 10 years, and follicular lymphoma is considered a slow growing cancer.