What Are the Different Antibiotics for Diverticulitis?


Quick Answer

The specific oral or IV antibiotic treatment for diverticulitis depends on the severity of the diverticulitis attack and the patient's ability to tolerate food. One-drug oral regimen options include Augmentin, doxycycline or moxifloxacin, reports the National Center for Biotechnology Information. Two-drug oral regimen options include Levaquin with ciprofloxacin or Bactrim combined with either Flagyl or clindamycin.

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Full Answer

If IV antibiotics are required, a regimen of cefoxitin, cefotetan, moxifloxacin, ampicillin/sulbactam, ampicillin clavulanate, piperacillin/tazobactam, ticarcillin/clavulanate, imipenem/cilastatin, meropenem or ertapenem is recommended by NCBI. Additionally, an IV regimen of aminoglycoside, third-generation cephalosporin, aztreonam, or a fluoroquinolone plus Flagyl or clindamycin as a treatment option is recommended. Patients are generally switched from IV to oral antibiotics when they can tolerate food. Antibiotic treatment generally lasts between seven and 10 days.

Rifaximin, a poorly absorbed antibiotic, is effective at relieving the symptoms of uncomplicated diverticular disease of the colon when compared with a fiber-supplemented diet, according to NCBI

The severity of diverticulitis is determined using the Hinchey Classification System, according to the NCBI. The Hinchey Classification system has four stages, with stage 4 being the most severe. Stage 1 and stage 2 diverticulitis cases are generally treated with diet and antibiotics, while stage 3 and stage 4 cases generally require surgery.

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