The major difference between Colgate and Crest toothpaste is that both brands have different toothpaste options available. Colgate has six options available, while Crest offers at least 10, with many additional sub-options. The most complete protection offered between the brands is Colgate Total Advanced Whitening and Crest Pro-Health Gum Protection, respectively.
The six options Colgate offers are: Advanced Whitening, Advanced Deep Clean, Advanced Fresh + Whitening, Clean Mint, Mint Strip and Whitening. Crest's options are: Pro-Health, 3D White, Baking Soda & Peroxide Whitening, Be Adventurous/Dynamic/Inspired, Cavity Protection, Complete Multi-Benefit, Pro-Health Stages, Kids, Plus Scope and Extra Whitening and Tartar Control.
Colgate's "complete protection" option, Total Advanced Whitening, claims to prevent plaque, bad breath, tartar build-up, gingivitis and cavities. Colgate also claims that it will remove surface stains up to 80%, while fighting germs for 12 hours. Colgate's toothpastes are all gluten free and have a sodium fluoride level of 0.24% with 0.14% fluroide ion.
Crest's "complete protection" option, Pro-Health Gum Protection, claims to fight sensitivity, cavities, tartar build-up, gingivitis and plaque, freshen breath and whiten teeth. It has 0.454% stannous fluoride with 0.16% fluoride ion. This means its whitening properties are likely to be stronger.
Colgate received FDA approval for the first gingivitis treatment from a toothpaste. Crest's use of stannous fluoride means that teeth can sometimes be badly stained by the toothpaste.