Moles are highly pigmented benign spots on the skin, whereas warts indicate a viral infection within the skin, according to The Health Success Site. Warts are caused by the human papillomavirus and can be passed to others through direct contact, according to Skin Speaks. While warts often contain no color, some types may appear dark, which allows it to be more easily confused with a mole.
Moles normally do not cause any trouble and seldom require medical treatment. However, it is vital to seek medical treatment in some cases. According to Skin Speaks, moles that are painful and irritated or those that bleed, crust, change shape, change color or change size are cause for concern, and Skin Speaks recommends that they should be evaluated by a medical professional or dermatologist.
Skin Speaks explains that there are several types of warts, including common warts, foot warts, flat warts and genital warts. Common warts usually grow on the fingers and hands. Foot warts occur on the soles of the feet and often appear in clusters. Flat warts grow anywhere and are smaller and smoother than other types of warts. While warts are not dangerous, the Health Success Site recommends that they should be evaluated and removed if they appear to be suspicious.