Deglycyrrhizinated licorice may help prevent stomach damage and soothe irritation caused by acid reflux, according to University of Maryland Medical Center. Use of deglycyrrhizinated licorice may also protect against stomach inflammation associated with the use of nonsteroidal anti-inflammatory drugs.
Licorice has been used since ancient times to treatment disorders of the digestive tract and other ailments, reports Healthline. However, long-term use of whole licorice can cause health problems for some individuals. Deglycyrrhizinated licorice has fewer side effects than whole licorice root because glycyrrhizic acid, the agent responsible for most side effects, has been removed, making it a safer option for most patients.