While manufacturers typically recommend daily doses of CoQ10 that range between 22 to 400 milligrams, 200 milligrams of CoQ10 taken daily for 12 weeks helps prevent heart disease, and 100 milligrams daily for 12 weeks treats Type 2 diabetes, reports Mayo Clinic. Doses up to 300 milligrams improve exercise performance.
When used as an antioxidant, 60 to 150 milligrams of CoQ10 taken daily for two to 12 weeks is the recommended dose, according to Mayo Clinic. Fibromyalgia is treated with 300 milligrams of CoQ10 taken daily, and 200 milligrams of CoQ10 taken as a single daily dose or divided into three doses is used to treat HIV/AIDS. Pregnant women with high blood pressure benefit from taking 100 milligrams of CoQ10 twice daily for 24 weeks prior to delivery.
CoQ10 offers protection to the heart during surgery when taken in doses of 100 milligrams per day for 14 days before and 30 days after surgery, notes Mayo Clinic. The supplement is helpful in lowering cholesterol in daily doses of 50 to100 milligrams taken for up to three months. When used in daily doses of 100 milligrams for three months, CoQ10 helps to promote weight loss, and a 1 percent CoQ10 cream applied to the skin for five months provides anti-aging properties.