Inguinal hernia, or swelling of the groin region, may lead to loss of blood supply to the intestines trapped in the abdominal muscles, according to the University of Rochester Medical Center. Inguinal hernias may also cause unbearable pain, reports Fox News. Swelling of the lymph nodes in the groin area can indicate cancer, urinary tract infection or infection from a sexually transmitted disease.
An indirect inguinal hernia is a condition whereby the opening in men through which testicles pass to the scrotum does not close during birth, as stated by the University of Rochester Medical Center. In women, the condition occurs if part of the small intestines or the reproductive organs slide to the groin area because of weak abdominal muscles. Direct inguinal hernias in men occur when the abdominal muscles become weak over time. A hernia strangulated in the abdominal muscles is a medical emergency requiring surgery.
Penile cancer and testicular cancer can cause swelling of the lymph nodes in the groin, as reported by Fox News. Urethritis, a bacterial or viral urinary tract infection that causes swelling and irritation of the urethra, can also lead to the enlargement of the lymph nodes in the groin, according to MedlinePlus.