D-ribose supplementation potentially improves the symptoms of fibromyalgia, according to About.com. This information comes from a 2006 study showing that symptoms such as low energy, pain and well-being all improved with D-ribose supplements.
Though more research is needed, some doctors recommend D-ribose supplements for their patients, and many patients find relief from fibromyalgia symptoms, claims About.com. D-ribose is considered safe for short-term use, but it does have side effects. These include headache, digestive issues and low blood sugar, so those with diabetes should avoid taking this supplement. There is no information available, as of 2015, if D-ribose is safe for women who are pregnant or nursing.