As of 2015, the cure for recurring urticaria includes daily doses of second-generation antihistamines such as loratadine, fexofenadine and cetirizine, according to the American Academy of Family Physicians. Studies show 35 percent of chronic urticaria patients are symptom-free within 12 months, and treatment reduces symptoms in about another 29 percent.
The key to treating chronic urticaria is avoiding known triggers, such as allergens, heat and cold, and substances such as alcohol and aspirin, notes the American Academy of Family Physicians. Urticarial symptoms in some patients may become worse if they use nonsteroidal anti-inflammatory drugs. In 48 percent of chronic urticaria patients with no known triggers, remission occurs spontaneously within 36 months. However, only 16 percent of those with physical urticaria experience remission without treatment.