A fungal foot infection, commonly known as athlete's foot, can be treated with an over-the-counter antifungal powder, spray or cream if the infection is a mild one, according to Mayo Clinic. Appropriate nonprescription drugs include Tinactin, Lamisil, Lotrimin-AF or Micatin. Cleveland Clinic instructs the patient to apply the product between all of the toes and to the top, bottom and sides of the affected foot or feet.
Cleveland Clinic further instructs the patient to continue to apply the medication twice a day for several weeks until the infection is completely healed. If the infection is more severe, Mayo Clinic states that a topical medication of prescription strength may be necessary. Topical medicines are applied directly to the skin and may be available in cream, gel, solution and lotion forms. Topical antifungals in prescription strength include Naftin, clotrimazole, econozole and Mentax, according to WebMD. One medication may be more effective for an individual than another.
WebMD emphasizes that it is crucial to continue to apply the medication on schedule for the entire time directed, even if the symptoms disappear. Symptoms are likely to return if treatment is stopped prematurely.
For severe cases of athlete's foot or when topical medications do not clear the infection, an oral prescription may be necessary, according to WebMD.