Abnormal lymphatic system functions are present in such conditions as Gorham-Stout disease and lymphangioleiomyomatosis, according to the National Organization of Rare Disorders. Intestinal lymphangiectasia is another condition where the lymphatic system behaves abnormally, says the Medical University of South Carolina Digestive Disease Center. In Gorham-Stout disease, the patient progressively loses bone because of the abnormal functioning of the lymphatic vessels, says NORD. The bones most affected by this disease include those of the spine, skull, pelvis, ribs and jaw.
Many people with Gorham-Stout disease also have a generalized lymphatic anomaly, or lymphangiomatosis, according to NORD. This disease can strike every bodily system save the central nervous system, says the American Lung Association. It causes benign tumors to grow in the part of the body it affects; the tumors are not cancerous, but they can be so numerous they interfere with the patient's daily life. Lymphangiomatosis usually strikes very young people, including babies. There is no cure for this disease.
Lymphangioleiomyomatosis, or LAM, is a disease that almost exclusively affects women of childbearing years, says WebMD. It mostly affects the lungs but can also affect the lymphatic system by blocking the flow of lymph with muscle cells. This is called chylous ascites, after the lymph fluid that accumulates in the patient's peritoneal cavity.
Intestinal lymphangiectasia is a disease where the lymph vessels are abnormally dilated, according to the MUSC Digestive Disease Center. Because the flow of lymph is reduced, the patient does not absorb nutrients the way he should.