Doctors prescribe a combination of triamterene and hydrochlorothiazide to treat high blood pressure, explains WebMD. They also prescribe it to help remove excess fluid from the body, a condition known as edema, in people with heart, liver or kidney disease.
Both triamterene and hydrochlorothiazide are diuretics, or what laymen often call "water pills." The combination of the two medicines helps the kidneys get rid excess water and salt without decreasing the body's potassium level, explains MedlinePlus. By controlling high blood pressure, these medicines help prevent damage to the heart, kidneys, blood vessels and brain that can lead to heart attacks, stroke, kidney failure and vision loss. In people with edema, they help decrease symptoms such as difficulty breathing and swelling in the ankles or feet, according to WebMD.