What Conditions Require a Daily Dose of 400 Mg of Magnesium Oxide?


Quick Answer

A daily dose of 400 milligrams of magnesium oxide is used to treat a duodenal ulcer, dyspepsia, gastric ulcer, gastroesophageal reflux disease and hypomagnesemia, according to Drugs.com. Pathological hypersecretory disorder and renal stones are also treated with approximately 400 milligrams per day.

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Full Answer

Magnesium oxide is an essential mineral that is used to treat low magnesium levels in the body due to restricted diet, malnutrition, alcoholism or magnesium-depleting drugs, explains Drugs.com. Because it neutralizes stomach acid, magnesium oxide is used as an antacid to treat heartburn, sour stomach and indigestion. It provides symptomatic relief from the hyperacidity associated with peptic esophagitis and hiatal hernia. Anticoagulants, such as warfarin, may interact with magnesium oxide, causing the drug’s side effects to increase. The effectiveness of penicillamine may be decreased by magnesium oxide.

The most common side effect of magnesium oxide is diarrhea, notes Drugs.com. Severe side effects include allergic reactions that involve rash, tightness in the chest, difficulty breathing, swelling of the mouth, face, lips, or tongue; slow reflexes; black, tarry stools; and vomit that looks like coffee grounds. The safety of magnesium oxide for children under age 6 has not been confirmed, and it is not known if it is found in breast milk.

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