Causes of middle chest pain include heart attacks and myocardial infarctions, states FamilyDoctor.org. If accompanied by palpitations, coughing, weakness and labored breathing, such pain may be a symptom of pericarditis, explains the National Heart, Lung, and Blood Institute. Generally, chest pains require immediate medical attention, notes Cleveland Clinic.
A myocardial infarction, a condition in which heart muscles die due to blockages in cardiac blood vessels, causes intense pain in the middle or the left side of the chest, according to WebMD. The pain cannot be relieved by rest and may be accompanied by weakness, perspiration and nausea.
Acute pericarditis, a condition characterized by irritation and swelling of the pericardium, the sac surrounding the heart, causes a sharp pain in the middle, left or front of the chest, explains the National Heart, Lung, and Blood Institute. Additionally, individuals with this condition may experience abdominal, shoulder, neck and back pain.
Chronic pericarditis is typically characterized by chest pain, states the National Heart, Lung, and Blood Institute. Advanced chronic pericarditis can lead to low blood pressure, a distended stomach and swollen feet. In addition, the condition may be accompanied by shortness of breath, coughing and tiredness. Pericarditis is associated with two dangerous complications. These are cardiac tamponade, a condition in which excessive fluid accumulates in the pericardium, and chronic constrictive pericarditis, a condition caused by development of scar tissue on the pericardium.