Chapped lips, cold sores, allergic reactions and conditions such as multiple sclerosis cause lips to tingle. Additionally, extreme heat or cold and exposure to toxic substances can lead to nerve damage that causes tingling lips, according to Healthgrades.
Hypoparathyroidism is a common condition that causes lips to tingle, states Mayo Clinic. Anxiety attacks lead to numbness or hyperventilation, resulting in tingling in the lips, around the mouth and hands, warns Drugs.com. Allergies and injuries cause sudden tingling of lips, whereas neuropathy and underlying nerve damage causes lips to tingle more frequently as the condition worsens over time, indicates Healthgrades. Seek prompt medical help if lip tingling is accompanied by numbness on one side of the body, a severe headache or loss of consciousness.