Benzoyl peroxide; topical retinoids such as adapalene and tretnoin; azelaic acid; and antibiotics are common treatments for skin acne, states WebMD. Typically, over-the-counter treatments should be tried before medications are prescribed.
Benzoyl peroxide cream or gel helps kill bacteria on the skin and prevent dead skin blocking follicles, states WebMD. The disadvantage of this treatment is that it has side effects such as itching, dry skin, burning, redness and increased sensitivity to sunlight.
Another treatment of skin spots is use of topical retinoids, which includes treatments such as adapalene and tretinoin cream or gels, states WebMD. These creams lower the production of a fatty secretion known as sebum and prevent dead skin cells blocking hair follicles.
Azelaic acid is a preferred treatment when retinoids and benzoyl peroxide cause serious side effects, according to WebMD. The cream is used to alleviate dead skin and bacteria.
Antibiotics applied to the skin, such as clindamycin and erythromycin, or taken as tablets, such as tetracycline, are effective in controlling surface bacteria, reports WebMD. However, they produce excellent results when used alongside benzoyl peroxide or retinoids.
Hormone therapy may also be effective in treating skin spots, especially in women, explains WebMD. The most common therapy involves a low-dose estrogen and cyproterone acetate.
Self-help care is also helpful in treating spots on the skin, states WebMD. For instance, the person is advised to wash the affected part only two times a day. Frequent washing is likely to worsen the symptoms. Mild soap and lukewarm water should be used in cleaning the spots; water that is too hot may worsen the symptoms.